micronized titanium dioxide

The global market for 30-50nm TiO2 powders is witnessing a rapid expansion, driven by the increasing demand for eco-friendly and energy-efficient solutions. As a result, manufacturers are constantly exploring new ways to optimize production, enhance functionality, and cater to diverse industry requirements. From tailor-made formulations for specific applications to exploring the potential of TiO2 nanoparticles in next-generation technologies, these manufacturers are at the forefront of shaping the future of nanomaterials.

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In a 2017 study published in Scientific Reports, researchers exposed rats to human-relevant levels of E171 to examine the effects of intestinal inflammation and carcinogenesis. They saw that “a 100-day E171 treatment promoted colon microinflammation and initiated preneoplastic lesions while also fostering the growth of aberrant crypt foci in a chemically induced carcinogenesis model.” They continued: “Stimulation of immune cells isolated from Peyer’s Patches [which are clusters of lymphoid follicles found in the intestine] showed a decrease in Thelper (Th)-1 IFN-γ secretion, while splenic Th1/Th17 inflammatory responses sharply increased,” researchers wrote. “A 100-day titanium dioxide treatment promoted colon microinflammation and initiated preneoplastic lesions.” The scientists concluded: “These data should be considered for risk assessments of the susceptibility to Th17-driven autoimmune diseases and to colorectal cancer in humans exposed to TiO2 from dietary sources.”

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